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Seitenaufrufe : 103608| CCDL/LFS |
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There are no translations available. CCDL - Coat Colour Dilution Lethal in Arabian Horses also known as LFS - Lavender Foal Syndrome What is CCDL/LFS? CCDL, also known as LFS is an autosomal recessive disease, which means that one copy of the disease gene is inherited from a carrier stallion and another from a carrier mare. The foal which inherits two copies of the disease gene is affected by severe neurological dysfunctions and usually dies within a few days of birth or is euthanized for humane reasons. Both male and female foals can be affected. What are the signs of CCDL/LFS? Lavender Foal Syndrome may appear similar to spinal cord injury or may be confused with perinatal asphyxia (lack of oxygen at birth), but is distinguished from these by the peculiar coat colour. Aside from the neurological signs, the most striking feature of this condition is the dilute or bleached-out hair coat colour. In a few cases, the colour is a very striking iridescent silver to pale lavender hue, hence the name "Lavender Foal Syndrome". "Coat Colour Dilution Lethal" is a more appropriate name, as many affected foals do not exhibit the striking lavender colour. Other dilute coat colours observed are pewter (pale slate grey) and pale chestnut (pink). At birth, most of these foals show involuntary contraction of muscels (tetany) with stiff legs and their heads and necks pulled backward (opisthotonus) as well as paddling with the legs. They are unable to assume sternal recumbency (lie upright) or stand. A foal may have a strong suckle reflex, in some cases involuntary, rapid eye movement (nystagmus) may be present. How can CCDL/LFS be avoided? The underlying defect causing this lethal disease is not known yet, currently there is no treatment for it and until an affected foal is born, there is no way of predicting which horses are carriers. |
